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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIA4
All Species:
23.64
Human Site:
Y446
Identified Species:
47.27
UniProt:
P48058
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48058
NP_000820.3
902
100871
Y446
G
N
D
K
Y
E
G
Y
C
V
D
L
A
S
E
Chimpanzee
Pan troglodytes
Q5IS46
956
107246
Y444
E
M
E
G
N
D
R
Y
E
G
F
C
V
D
M
Rhesus Macaque
Macaca mulatta
XP_001101297
902
100838
Y446
G
N
D
K
Y
E
G
Y
C
V
D
L
A
S
E
Dog
Lupus familis
XP_851091
902
100907
Y446
G
N
D
K
Y
E
G
Y
C
V
D
L
A
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2W8
902
100613
Y446
G
N
D
K
Y
E
G
Y
C
V
D
L
A
S
E
Rat
Rattus norvegicus
P19493
902
100739
Y446
G
N
D
K
Y
E
G
Y
C
V
D
L
A
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509465
890
99579
Y434
G
N
D
K
Y
E
G
Y
C
V
D
L
A
S
E
Chicken
Gallus gallus
P19439
487
54337
P36
N
D
D
A
M
I
K
P
N
D
L
R
G
P
E
Frog
Xenopus laevis
Q91756
479
53388
I28
A
G
E
S
K
G
S
I
H
K
E
K
E
R
S
Zebra Danio
Brachydanio rerio
Q68Y21
1009
113606
V456
L
E
E
P
F
V
M
V
S
E
N
V
L
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03445
991
111650
L531
G
I
K
Y
E
I
R
L
V
Q
D
G
N
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34299
962
108124
N489
N
L
T
E
C
Q
G
N
N
K
F
E
G
F
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.2
99.7
99.5
N.A.
98.3
98.2
N.A.
91.4
21.7
22.5
28.1
N.A.
39.1
N.A.
36.1
N.A.
Protein Similarity:
100
50.2
99.7
99.7
N.A.
98.5
98.5
N.A.
94.4
34.3
35.2
46.8
N.A.
56.9
N.A.
53.9
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
13.3
0
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
20
13.3
33.3
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
0
0
0
0
0
50
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
50
0
0
9
0
0
9
% C
% Asp:
0
9
59
0
0
9
0
0
0
9
59
0
0
9
0
% D
% Glu:
9
9
25
9
9
50
0
0
9
9
9
9
9
0
59
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
17
0
0
9
0
% F
% Gly:
59
9
0
9
0
9
59
0
0
9
0
9
17
9
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
17
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
50
9
0
9
0
0
17
0
9
0
0
9
% K
% Leu:
9
9
0
0
0
0
0
9
0
0
9
50
9
0
0
% L
% Met:
0
9
0
0
9
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
17
50
0
0
9
0
0
9
17
0
9
0
9
0
0
% N
% Pro:
0
0
0
9
0
0
0
9
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
17
0
0
0
0
9
0
9
0
% R
% Ser:
0
0
0
9
0
0
9
0
9
0
0
0
0
50
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
9
9
50
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
50
0
0
59
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _